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24-29 January 2010 Wellcome Trust Genome Campus, Hinxton, Cambridge Deadline for applications: 23 October 2009 Course summary The overall aim of this course is to provide practical, laboratory-based training for clinical scientists, specialist registrars and consultants in medical microbiology (including joint medical microbiology and infectious diseases) in the application of current genetic techniques to the general medical microbiology laboratory. The course will be planned around a theme of using genetic techniques to identify the source of an outbreak. Bacteriology (rather than virology) will be the focus. The course programme will consist of hands-on laboratory training complemented by lectures and guest-speaker seminars. PLEASE NOTE: bursaries are available for clinical and academic applicants from anywhere in the world to attend this course, see below for details. This includes bursaries for UK registrars. In addition, CPD accreditation (41 credits) was approved by the Royal College of Pathologists in 2009. A similar application will be submitted for the 2010 course. Programme 1. Isolate characterisation at the molecular level (lead: Professor Martin Maiden Sequence based methods/MLST Databases and data analysis. 2. VNTR (lead: Dr Cath Arnold) Choosing the correct method Molecular techniques used, including VNTR analysis SNPs Real-time PCR Data analysis/interpretation. 3. 16sRNA (lead: Professor Stephen Gillespie) Choosing the correct specimen PCR and primers Cloning Assigning a species identification Interpretation of the result to the clinician. 4. Real-time PCR Sample extraction Molecular techniques used Real-time PCR platform choice Multiplex assay development Data analysis/interpretation 5. Bioinformatics Sequence search and comparison programs Interpretation of results. Areas/issues that will be addressed in practicals, demonstrations or lectures: specimen collection and contamination problems technique discrimination - demonstrate how to choose the appropriate technique case studies demonstrating the benefits of 'genetics' over 'culture'. Course instructors Professor Martin Maiden (University of Oxford) Professor Stephen Gillespie (University College London) Dr Cath Arnold (Health Protection Agency) Invited speakers 2009 (2010 speakers TBC shortly) Professor Julian Parkhill (Wellcome Trust Sanger Institute, UK) Dr Xavier Nassif (Unit? de Pathog?nie des Infections Syst?matiques, France) Dr Helen Lee (University of Cambridge, UK) Dr Ulrich Vogel (Institute for Hygiene and Microbiology, Germany) Professor Mark Achtman (University College Cork, Ireland) CPD Accreditation CPD accreditation (41 credits) was approved by the Royal College of Pathologists in 2009. A similar application will be submitted for the 2010 course. Cost The course is subsidised by the Wellcome Trust. This is a residential course, without exception, and there is a fee of ?675 towards board and lodging for clinical and academic applicants. The fee for commercial (non-academic) applicants is ?3050. Bursaries Bursaries are available for clinical and academic applicants (50 per cent of fee) and are subject to open competition. Applications Applicants must complete an application form containing a detailed outline of the relevance of the course to their clinical work. Please note that documentation supporting their application will be required from the applicant's supervisor/head of department Bursaries for Wellcome Trust Advanced Courses The Wellcome Trust subsidises all courses and workshops, so there are no tuition fees. The ?course fee' for the UK courses (held at Hinxton) covers on-site accommodation and food for the duration of the course. Bursaries are available to assist with UK course fees, but not travel costs. We are committed to building scientific capacity in developing countries and are expanding the number of courses and workshops run outside of the UK (?overseas' courses). There is no fee for these courses and bursaries are available f

24-29 January 2010 Wellcome Trust Genome Campus, Hinxton, Cambridge Deadline for applications: 23 October 2009 Course summary The overall aim of this course is to provide practical, laboratory-based training for clinical scientists, specialist registrars and consultants in medical microbiology (including joint medical microbiology and infectious diseases) in the application of current genetic...

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